Nature’s Toolbox (NTx), a life sciences company developing next-generation platforms for RNA and protein manufacturing, today launched NTx Services. This new service produces high-integrity complex mRNA using the innovative NTxscribe® RNA manufacturing system. NTx Services offers faster turnaround, more flexibility, and scalability than traditional mRNA production processes by leveraging the NTxscribe continuous flow in vitro transcription (IVT) system.
NTx Services is offering access to the research grade mRNA manufacturing capabilities of the NTxscribe system ahead of the commercial launch of its next generation device early next year. NTxscribe can produce 50mg of high-integrity mRNA in just one hour with the push of a button, allowing NTx Services to deliver mRNA constructs faster than standard service providers. NTx Services is flexible and scalable, capable of producing milligram to gram quantities of consistently high-integrity mRNA or saRNA from 2,000kb to 14,000nt+. Additionally, NTx Services offers lower price points for consistently high-integrity mRNA or saRNA constructs compared to current batch method chemistry approaches from other service providers.
“At NTx, our mission is to revolutionize mRNA manufacturing by making it more accessible, dependable, scalable, and cost-effective with our cutting-edge continuous flow IVT technology,” said Dr. James Coffin, President and CEO of NTx. “Our system not only reduces costs and simplifies the process, but also eliminates harmful byproducts, making it significantly more sustainable than traditional batch methods. Any research or development program focused on RNA-based vaccines or therapies that demands ultra-pure, high-quality mRNA can significantly accelerate clinical trials, commercialization, and scaling by partnering with NTx Services.”
NTx Services is powered by NTxscribe, a benchtop plug-and-play continuous flow mRNA IVT and purification system built on NTx’s technology platform for RNA manufacturing. NTxscribe is a first-of-its-kind IVT system that enables the production of RNA in a fraction of the time and cost compared to traditional IVT, using a proprietary hollow fiber bioreactor in conjunction with continuous flow principles. Designed as a single-use functionally closed system, NTxscribe incorporates integrated process analytic technologies for real-time process monitoring. The biosynthetic platform offers a low cost, rapidly deployable, and vertically integrated manufacturing system, which allows mRNA manufacturing to scale from research and development quantities to commercial levels with a compact, economical footprint.
The next generation of NTxscribe devices will be directly available through an early access program later this year, with a projected commercial launch in the first quarter of 2025.
For more information about NTx Services, please visit: https://www.ntxbio.com/mrna-services/.
About NTx
Nature’s Toolbox, Inc. (NTx) is advancing the healthcare industry with their next generation biomanufacturing solutions. NTx, based in Rio Rancho, New Mexico, is developing innovative systems like NTxpress® and NTxscribe® to enable manufacturing of mRNA vaccines and protein therapeutics in an eco-friendly and sustainable way. These easily scalable processes enable NTx’s platform to scale from personalized medicine dosage to pandemic volume. To learn more about their game-changing approach, visit their website at https://www.ntxbio.com.
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